Sodium tetradecyl sulfate is an anionic surfactant which occurs as a white, waxy solid. The structural formula is as follows: C14H29NaSO4 7-Ethyl-2-methyl-4-hendecanol sulfate sodium salt MW 316.44. ... INDICATIONS & USAGE. Sotradecol (sodium tetradecyl sulfate injection) is indicated in the treatment of small uncomplicated varicose veins of ...

Sodium tetradecyl sulfate; Adult Indications & Dosage: Pediatric Indications & Dosage: Contraindications: Warnings & Precautions: Adverse Reactions: Drug Interactions: ... Sodium tetradecyl sulfate is a sclerosing Agent that is FDA approved for the treatment of small uncomplicated varicose veins of the lower extremities.

It is a sterile aqueous injection of Sodium Tetradecyl Sulfate (STS), an anionic detergent. It has been used in the treatment of varicose veins since 1946. Fibrovein is manufactured under cGMP conditions and complies with all EU regulations. The product was first registered in the UK in 1967 when it was marketed under the name of STD injection.

Sodium Tetradecyl Sulfate 4/5. Consumer Information Use and Disclaimer This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential

In the rat, the acute intravenous LD 50 of sodium tetradecyl sulfate was estimated to be between 72 mg/kg and 108 mg/kg. Purified sodium tetradecyl sulfate was found to have an LD 50 of 2 g/kg when administered orally by stomach tube as a 25% aqueous solution to rats. In rats given 0.15 g/kg in drinking water for 30 days, no …

A Prospective Clinical Trial Evaluating the Efficacy of 1.5% Sodium Tetradecyl Sulfate Injection for the Treatment of Epidermoid Cysts The objective of this study is to determine the efficacy, safety, tolerability, and patient satisfaction associated with the treatment of epidermoid cysts with injected 1.5% sodium tetradecyl sulfate …

TROMBOVAR® Therapex Sodium Tetradecyl Sulfate Sclerosing Agent. Indications And Clinical Uses: Sclerosing treatment of varicose veins in the legs, using compression sclerotherapy. Contra-Indications: Incompetency of collateral deep veins in the legs; incompetency of the valves of the greater and lesser saphenous veins before ligation of …

Sodium tetradecyl sulfate, a synthetic surfactant (soap), is an FDA-approved sclerosant. It is commercially available in 1% or 3% standard concentrations. This sclerosant is reliable, safe, and effective. ... The elements of the consent should include the indications for sclerotherapy, available alternative treatments, potential complications ...

PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice

uses. What is Sodium Tetradecyl Sulfate (Sotradecol) used for? Varicose Vein. warnings. What is the most important information I should know about Sodium Tetradecyl Sulfate...

Sodium tetradecyl sulfate (STS) is an anionic surfactant used in the sclerosant drug Sotradecol. It is commonly used in the treatment of varicose and spider veins of the leg, during the procedure of sclerotherapy. ... Indication : Varicose veins; Treatment of upper GI bleeding due to esophageal varices. Contraindications : Hypersensitivity ...

Sodium tetradecyl sulfate is a sclerosing (skler-OH-sing) agent. It works by increasing the formation of blood clots and scar tissue inside certain types of veins. This helps decrease dilation of enlarged veins. Sodium tetradecyl sulfate is used to treat small uncomplicated varicose veins in the legs.

Sodium tetradecyl sulfate should only be administered by a physician familiar with the diagnosis and treatment of conditions affecting the venous system and with the proper injection technique. Extravasation may result in severe local adverse reactions including necrosis. Extreme care in needle placement and use of the minimal effective …

polidocanol, Varithena, sodium tetradecyl sulfate, Asclera Indications and Usage for Sotradecol. Sotradecol (sodium tetradecyl sulfate injection) is indicated in the treatment of small uncomplicated …

Sodium tetradecyl sulfate injection is used to treat small varicose veins of the lower legs. It is a type of medicine called a sclerosing agent. This medicine is to be given only by or …

pain, itching, peeling, skin sores, or skin changes where the medicine was injected. Common side effects of Sotradecol may include: mild headache; nausea, vomiting; or. discolored skin along the treated vein (may be permanent). This is not a complete list of side effects and others may occur. Call your doctor for medical advice …

Sodium tetradecyl sulfate is an anionic surfactant which occurs as a white, waxy solid. The structural formula is as follows: C14H29NaSO4 7-Ethyl-2-methyl-4-hendecanol sulfate sodium salt MW 316.44. Sotradecol (sodium tetradecyl sulfate injection) is a sterile nonpyrogenic solution for intravenous use as a sclerosing agent.

Generally use 1% solution; 3% solution preferred for larger varicosities. 5–20 mg of the 1% sodium tetradecyl sulfate solution (0.5–2 mL, preferably ≤2) or 15–60 mg of the 3% sodium tetradecyl sulfate solution (0.5–2 mL, preferably ≤2) recommended by manufacturer for each injection site. Do not exceed 2 mL per injection site or 10 ...

Sodium tetradecyl sulfate is a medication used to treat small uncomplicated varicose veins in the lower limbs. Varicose veins are superficial, twisted, enlarged veins that appear just below the skin surface, and cause pain and discomfort. Sodium tetradecyl sulfate is injected into different sites along the swollen vein, which blocks blood flow into …

Dosages of Sodium Tetradecyl Sulfate: Dosage Forms and Strengths. Injectable Solution. 1%. 3%. Dosage Considerations – Should be Given as Follows: Venous Varices. May administer a test dose of 0.5 mL several hours before treating with larger doses. 0.5-2 mL intravenously (IV) (preferably 1 mL) in each vein; 1% solution for general use and 3% ...

Medscape - Indication-specific dosing for Sotradecol, Trombovar (sodium tetradecyl sulfate), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. News …

Fibrovein containing sodium tetradecyl sulfate is administered directly into the lumen of the isolated segment of vein/venule. Distribution In humans, the majority (75 %) of an injected dose of radiolabelled 3 % sodium tetradecyl sulfate rapidly disappeared from the empty varicose vein injection site into communicating blood vessels with rapid ...

sodium tetradecyl sulfate sodium sotradecol sotradecol tetradecyl sulfuric acid ... indication: 128060009: DOID:799: Incompetence of any valvular structure: contraindication: 10337008: Infection of skin AND/OR subcutaneous tissue: contraindication: 19824006: Peripheral venous insufficiency:

Sodium tetradecyl sulfate, a drug approved by the FDA for the treatment of varicose veins of lower extremities, makes the submucosal tissue fibrotic, and then fixes the hemorrhoidal tissue. The common method of sclerotherapy is to inject 0.5–2.0 mL of 1% sodium tetradecyl sulfate or 5% phenol under the mucosa at the top of the …

The guideline gives recommendations concerning indications, contraindications, side-effects, con … This guideline focuses on the two sclerosing drugs which are licensed in the majority of the European countries, polidocanol and sodium tetradecyl sulphate. Other sclerosants are not discussed in detail. The guideline gives recommendations ...

Abstract. Background: Sodium tetradecyl sulfate (STS) is Food and Drug Administration approved for treatment of varicose veins, but numerous other off-label applications have …

Background: Sodium tetradecyl sulfate (STS) is Food and Drug Administration approved for treatment of varicose veins, but numerous other off-label applications have been reported. Objective: To describe the clinical uses of STS, as well as efficacy and adverse effects. Methods: Review of studies searchable on PubMed from 1938 to 2016 …

Includes Sodium Tetradecyl Sulfate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. ... Avoid using sodium tetradecyl sulfate ed with room air; safety and efficacy has not been established. Thromboembolism: Deep ...

Sodium tetradecyl sulfate is 7-ethyl-2-methyl-4-hendec-anol sodium sulfate (C14H29NaSO4). It is a synthetic an-ionic surfactant that is available as 1% and 3% aqueous solutions with 2% benzyl alcohol and is buffered to a pH of 7.9 with sodium phosphate.1,4It is packaged in 2-mL. TABLE 1. Sclerosants. Volume, mL.

4.1 Therapeutic indications Fibrovein 3% and 1%: For the treatment of varicose veins of the leg by injection sclerotherapy. Fibrovein 0.5%: For the treatment of varicose veins and venous flares of the leg by injection ... • Hypersensitivity to sodium tetradecyl sulphate or to any component of the preparation and allergic conditions.